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The National Autonomous University of Mexico (UNAM) is the largest university in Latin America, with over 270,000 enrolled students. It is credited with educating a number of Mexican presidents as well as prominent Latin American academics. In 1999, students attending UNAM paid approximately $0.02 for semester tuition.

In 2004, Governor Ulises Ruiz Ortiz became Governor of Oaxaca in a contentious election, rumored to involve fraud.  Many civilians and activists were angered over his win and led protest campaigns against him, resulting in the detention, incarceration, and disappearance of hundreds of social leaders throughout Oaxaca.  State forces silenced those who attempted to demonstrate even though the Oaxacan constitution permits protest.